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MOLECULAR MECHANISMS OF REDOX REGULATION IN INFLAMMATION
We are hopeful that TVALA will reduce p53 expression in people with ALS. There are two recent publications that give us hope. The first paper is by Maor-Nof et. al. (2022), found in Cell. The found that p53 ablation protects neurons from axonal degeneration and cell death caused by C90rf72 expansion. Further, p53 ablation extends the lifespan in a mouse model of C9orf72. The literature references p53 as a driver of ALS in both familial and sporadic ALS. Reducing p53 protei
Dec 19, 20232 min read
White Paper Issue 17: Effectiveness of levamisole HCl and thymalfasin in two mouse models of ALS
Levamisole HCl and Zadaxin tested in two mouse models of ALS
Apr 6, 20223 min read
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