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Finding
Hope.

Neurodegenerative Disease Research 

funded novel research in an effort to directly benefit patients suffering from neurodegenerative diseases.

Brain Scans

It's time we moved the needle in ALS research.

NDR identifies promising research programs that break from tradition.

 

This novel research is helping to identify the causes of ALS, the phase of disease progression, and developing targeted treatments to end neurodegeneration.

Funded Novel Research

We're committed to finding a cure for ALS. That's why we work with researchers who are thinking outside-the-box to develop treatments.

Bringing Hope

NDR never loses sight of who we're fighting for: those affected by ALS. Every day, our unique approach is moving us closer to definitive treatment to extend quality of life for ALS patients.

Connecting Scientists

Our open forum allows the free exchange of information. We believe openness and transparency are the only ways we're going to beat ALS.

Identifying the Cause

NDR and our partners in research understand that treatments are only effective if the root cause of the disorder is known. Researchers are working around the clock to identify specific biomarkers responsible for ALS.

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Light microscope of Motor neurons of the spinal cord are part of the central nervous syste

What is ALS?

The course of ALS is death of motor neurons in 3 to 5 years, in some unusual cases 10-18 years from diagnosis. In those years the body transforms merely to skin stretched over bone; muscles disappear, limbs fail, and paralysis ensues. All the while, the mind is present and aware.

Over 5,000 people are diagnosed with amyotrophic lateral sclerosis (ALS) annually. NDR is funding novel research and drug development to bring that number to zero.

Science-based Hope

Rather than treating the symptoms of ALS, NDR and funded researchers are working toward a definitive treatment and cure for ALS. 

This requires out-of-the-box thinking, 24/7 dedication, and a science-based approach to identify the cause of ALS.

 

Only when we get to the root cause of this disease will we actually be able to effectively treat ALS patients.

Modern Medical Research Laboratory_ Two Scientists Working, Using Digital Tablet, Analyzin

The NDR Approach

Disease Detection & Biomarker Discovery

Drug screening, repurposing, & synergy

ALS treatment clinical trials 

Sci-hope
Colored Motor Neuron under the microscope in Lab..jpg

NDR Impacts in ALS Research

Viral Drug Delivery for Proteosome Therapy

Cell-based Assays for Drug Testing

Over 150 Antibody Probes for Phosphosites in Neuroprotein Targets in ALS

Benefits to ALS Patients

Secretome cGMP Production & Clinical Trial Development

Pre-clinical Trial Development for Treatments:
TVALA
 & Imatinib

Drugs Repurposed for Treatment of Neuroinflamation in ALS:
Suramin & Zadaxin

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