ndralsresearchApr 63 minWhite PapersEffectiveness of levamisole HCl and thymalfasin in two mouse models of ALSLevamisole HCl and Zadaxin tested in two mouse models of ALS
NDRMar 314 minWhite PapersWhite Paper Issue 16: Seeing ALSCould optical coherence tomography be useful in stratifying ALS patients? Ocular nerves are specialized connections to the central...
NDRMar 274 minWhite PapersWhite Paper 15: Are in vitro Neuronal Cells Models for ALS discovery?in vitro neuronal cells considered for ALS drug discovery
NDRMar 26 minWhite PapersWhite Paper Issue 14: Utility to Futility: Zilucoplan fails in human ALS trial Thomas Edison famously said, “I haven’t failed—I’ve just found 10,000 that won’t work.” Unfortunately, that is the state of the art for...
NDRFeb 173 minWhite PapersWhite Paper Issue 13: NDR’s Roadmap to an ALS CureFinding a cure for ALS is a lofty goal shared by all those involved in the field. The differences between the organizations that support...
NDRJan 103 minWhite PapersNDR White Paper Issue 11: Mechanisms of common pathologies in ALSDespite the initial cause, all cases of ALS, familial or sporadic, follow a final common pathogenesis. The ability for the body to...
NDRJan 74 minWhite PapersNDR White Paper Issue 10: Genetics and ALSIn Ancient Egypt a person’s essence or soul was passed to their descendants, symbolized by Ka. Amyotrophic lateral sclerosis (ALS) has...
NDRJan 5, 20211 minWhite PapersWhite Paper 9: Stress Response in ALS: Dr. Robert NaviauxResearch in our lab has led to a new understanding of the ancient biology that underlies the circle of injury and recovery. New medicines...
NDRDec 26, 20204 minWhite PapersNDR White Paper Issue 8: ALS and epigeneticsNothing illustrates that change is the essence of life quite like the butterfly. How does this cloudless sulphur caterpillar, eating the...
NDRNov 20, 20207 minWhite PapersNDR White Paper Issue 7: Models of ALSCathleen Lutz (Jackson Laboratory) described ALS as a “complex disease and consists of a group of conditions unified by a common theme,...
NDRNov 5, 20204 minWhite PapersNDR White Paper Issue 6: Energy MetabolismNDR is approaching ALS from multiple directions- currently we have 17 active projects! What is fascinating is the emerging overlap...
NDRAug 28, 20203 minWhite PapersNDR White Paper Issue 5: Activity of ThymosanImmunonormalizing molecules thymopoietin and levamisole HCl Inflammation and regulation of inflammatory responses are necessary for life....
NDRAug 4, 20204 minWhite PapersNDR White Paper Issue 4: C9orf72RAN Proteins The discovery of a repeat expansion1 in the C9orf72 gene is important because it is a model to explain central...
NDRMay 15, 20203 minWhite PapersNDR White Paper Issue 3: Adipose & SecretomeThe role of fat cells in treatment of ALS Amyotrophic lateral sclerosis is a (heterogeneous) neurodegenerative disorder with a variable...
NDRMay 7, 20205 minWhite PapersNDR White Paper Issue 2: Treatments Are LackingNDR’s goals are simple, bring promising therapies to ALS patients and know which treatment is appropriate for a patient by evaluating...
NDRMay 1, 20203 minWhite PapersNDR White Paper Issue 1: ThymopoietinAmyotrophic lateral sclerosis (ALS) is a motor neuron disease of animals and man with life-altering consequences. The defining pathology...